Coronavirus Update 116: Pfizer COVID 19 Vaccine Explained (Biontech)

Professor Roger Seheult, MD discusses the Pfizer / Biontech COVID-19 mRNA vaccine: How it works and what we know about the safety and efficacy at this time. No mRNA vaccine has ever been approved by the FDA, but Pfizer and BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trial. This two-dose vaccine regimen has limitations including the need for -70 C refrigeration and many questions remain: Will the vaccine prevent transmission and asymptomatic spread? How long will immunity last? Will “90% effective” hold up to peer-review and additional data when it is gathered? (This video was recorded on November 12, 2020). Dr. Seheult is the co-founder and lead instructor at https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Coronavirus+Update+116%3A+Pfizer+COVID+19+Vaccine+Explained+%28Biontech%29&utm_content=_jwBxZMWrng LINKS / REFERENCES: Johns Hopkins Tracker | https://coronavirus.jhu.edu/map.html Worldometer | https://www.worldometers.info/coronavirus/ COVID-19 vaccine tracker (RAPS) | https://www.raps.org/news-and-articles/news-articles/2020/3/covid-19-vaccine-tracker Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates (NEJM) | https://www.nejm.org/doi/full/10.1056/NEJMoa2027906 A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates (bioRxiv) | https://www.biorxiv.org/content/10.1101/2020.09.08.280818v1.full.pdf Pfizer and BioNTech Announce Vaccine Candidate Against COVID-19 Achieved Success in First Interim Analysis from Phase 3 Study (BioNTech) | https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-announce-vaccine-candidate-against-covid-19 Why mRNA represents a disruptive new drug class {BioNTech) | https://biontech.de/how-we-translate/mrna-therapeutics THE MEDCRAM WEBSITE: Visit us for videos on over 60 medical topics and CME / CEs for medical professionals: https://www.medcram.com/?utm_source=Youtube&utm_medium=Video&utm_campaign=Video+Link+Clicks&utm_term=Coronavirus+Update+116%3A+Pfizer+COVID+19+Vaccine+Explained+%28Biontech%29&utm_content=_jwBxZMWrng SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL: /user/MEDCRAMvideos Get notified of new videos by hitting the bell icon: RECENT PREVIOUS COVID-19 UPDATES: Please visit MedCram.com for the full series: - Coronavirus Update 115: Convalescent Plasma vs Monoclonal Antibodies for COVID 19 Treatment /watch/UnWrzf4T8eGTr - Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine) Data /watch/gtx-8BP1OQe1- - Coronavirus Update 113: Remdesivir May Not Work for COVID 19 /watch/8G2FyFpQdUmQF - Coronavirus Update 112: Linoleic Acid; Vaccines; UK COVID 19 Data /watch/Iz79AVu60BV69 - Coronavirus Update 111: Masks; New Vitamin D Data and COVID 19; NAC /watch/8QTdjuqKGzUKd - Coronavirus Pandemic Update 110: Trump's Risk Factors and COVID-19 Prognosis; Interferon /watch/40nPmGx2okR2P - Coronavirus Pandemic Update 109: New Data From Europe As COVID 19 Infections Rise /watch/gbekcC63HCr3k - Coronavirus Pandemic Update 108: High Risk COVID 19 Behaviors; Cases Rise in Europe /watch/geKTt5BdJw2dT - Coronavirus Pandemic Update 107: Monoclonal Antibodies for COVID 19 Treatment and Prevention? /watch/Mhj8pxyLavwL8 - Coronavirus Pandemic Update 105: FDA Authorized Treatments; COVID 19 Vaccine Update /watch/sPO7poRRM10R7 - Coronavirus Pandemic Update 103: Convalescent Plasma Treatment & the FDA; College Campuses Close /watch/wa4VX_TtmvptV All coronavirus updates are at MedCram.com (including monoclonal antibody treatment vs convalescent plasma treatment, COVID vaccine, COVID 19 prevention, Pfizer vaccine, Biontech, coronavirus vaccine, COVID 19 treatments, COVID-19 vaccine updates, and more). We offer over 60 medical topics (ECG Interpretation, DKA, influenza, measles, mechanical ventilation, etc.) on our website. MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS: MedCram offers group discounts for students and a variety of medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested. MEDIA CONTACT: Roger Seheult, MD Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. Associate Professor at the University of California, Riverside School of Medicine Media Contact: customers@medcram.com Media contact info: https://bit.ly/3q2ErVv Video Produced by Kyle Allred FOLLOW US ON SOCIAL MEDIA: https://www.facebook.com/MedCram https://twitter.com/MedCramVideos https://www.instagram.com/medcram DISCLAIMER: MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor. #COVID19 #SARSCoV2

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